Pieter Roelfsema

Professor of Neurobiology; director of the Netherlands Institute for Neuroscience (NIN); leader of the Vision & Cognition group; co-founder of phosphoenix. The scientific backbone of the modern cortical visual prosthesis field.

Background

  • NIN (KNAW, Amsterdam): director; Vision & Cognition group — cortical mechanisms of visual perception, memory, plasticity, attention; visual prosthesis development (“aiming to restore a rudimentary form of sight”, per CCN 2025 keynote bio).
  • Coordinator of the Dutch neurotechnology initiative NeuroTech-NL.
  • (2019) co-founded Phosphoenix (with Xing Chen and Bert Monna) — see phosphoenix — the spin-off translating NIN’s macaque work to a clinical device.
  • Leads EU-funded research programs supporting visual prosthetics (incl. the Dutch contribution to high-density implants).

The breakthrough

With Xing Chen (lead author), Eduardo Fernández and Fei Wang: “Shape perception via a high-channel-count neuroprosthesis in monkey visual cortex” (Science, Dec 2020) — a 1024-channel prosthesis in monkey V1+V4; phosphene percepts matched receptive fields; simultaneous multi-electrode stimulation generated percepts recognized as shapes, motion, letters. This demonstrated the theoretical feasibility of functional cortex-driven form vision and changed the field’s expectations for electrode count (see Perspective by Beauchamp & Yoshor).1

Why it matters

Roelfsema’s lab provides the science behind the EU cortical challenge: while retinal devices (PRIMA) achieved commercial form vision, cortex prostheses can work for any blindness cause. His group’s 1024-channel results, plus the clinical evolution to LGN targeting via Phosphoenix, define the current state of “can you actually see via the brain” — the frontier that Neuralink Blindsight, ReVision and Orion (see cortical-visual-prosthesis-companies) are racing to translate.

References

  • ORCID: https://orcid.org/0000-0002-1625-0034
  • CCN 2025 keynote bio; NIN Roelfsema group page; Science 370(6521):1191-1196 (2020).
  • BioGeneration Ventures PR (2022-09-22) — Phosphoenix founders.

Footnotes

  1. raw/papers/chen-2020-shape-perception.md